Presence Of Increased Stiffness Of The Common Carotid...

Study Design: Case-Control Study Title: Presence of increased stiffness of the common carotid artery and endothelial dysfunction in severely obese children: A prospective study Journal: The Lancet Numerous epidemiological studies infer that cardiovascular complications have a directly proportional relationship with obesity in children. The study I chose however, has gone deeper by observing arterial changes as well as its relationship to cardiovascular risk in children who are obese. One of the reasons this study design was chosen by the author comes from a 55-year cohort study which evaluated the morbidity and mortality from cardiovascular diseases in adults who were overweight in their adolescent years. The study showed that of the adults evaluated, the adults with obesity in their adolescent years had an increased risk of morbidity and mortality from cardio vascular disease, regardless of their weight classification as an adult. What these studies did not observe however, were the pathological changes that take place in the cardiovascular system, and even more specifically how obesity-associated artherogenesis develops during the adolescent years. Fortunately, with the dev elopment of new technology, different echo tracking procedures could be used to observe the pathological function of the carotid and brachial arteries and children. These new echo tracking techniques are noninvasive and can be used to determine if overweight children show early pathologicalShow MoreRelatedVascular Endothelial Growth Factor ( Vegf )2305 Words   |  10 Pagesuveitis, vas-cular manifestations and other multisystem affections [1,2]. Vasculitis causes endothelial destruction and thrombosis [3]. Inflammatory thrombosis is well-known in BD [4]. It has been recognized that vascular endothelial dysfunction occurs in BD and plays a substantial role in the vascular lesions. The path-ogenic mechanism is uncertain [5]. There are several identified vascular endothelial growth factor (VEGF) family members: VEGF (VEGF-A), VEGF-B, VEGF-C, VEGF-D and placenta growthRead MoreEssay On HIV700 Words   |  3 PagesStein et al. (2015) similarly conducted a prospective, randomized clinical trial comparing effects of three ART treatments on carotid wall intima-media thickness (IMT). This was a multicenter project taking place over 26 institutions and included a total 328 participants. Subjects included HIV infected individuals who were not on any ART regimen and did not have known cardiovascular disease or diabetes mellitus. Participants who reported use of statins, fish oil, fibric acid derivatives or niacinRead MoreAcute Heart Failure ( Chf )1865 Words   |  8 PagesOne of the main causes of mortality and morbidity is congestive heart failure (CHF). The major causes of CHF are coronary artery disease and hypertension. Other risk factors are occurrence of left ventricular hypertrophy (LVH), valvular heart disease, diabetes, smoking, obesity and dyslipidemia [46, 47]. Diabetes mellitus as an anticipated factor of CHF was explained in some studies [44, 47]. Diabetes is considered as a risk factor for CHF but yet, its relationship with CHF has not been completelyRead MoreReport: Immobility Due to Cerebrovascular Accident3338 Words   |  13 Pagespatient suffering from immobility due to Cerebrovascular Accident (CVA). The paper explores the necessary care that is necessary to help the patient cope with the situation while preserving his dignity. Introduction Immobility is one of the most common complications in stroke patients (Doshi, Say, Young, Doraisamy,2003).It is important for stroke patients who suffer from immobility problems to be taken care of appropriately. This is because immobility due to stroke may predispose a patient to deepRead MoreNU 545 Unit 2 Essay10921 Words   |  44 Pagesvilli. 3. Where is the primary defect in Parkinsons disease and Huntingtons? - (Pg 459) The inferior most portion of the basal ganglia is the substantia nigra, which synthesizes dopamine, a neurotransmitter and precursor of norepinephrine. Its dysfunction is associated with Parkinson’s disease. Parkinsons and Huntington’s are both defects of the basal ganglia. P. 564-565 ! 4. What is the function of the CSF? Where is it produced? Where is it absorbed? - (Pg 465) Cerebrospinal fluid (CSF)